Collaboration to investigate delivery of SuliXen, Lipoxen’slong-acting insulin candidate for Type 1 and Type 2 diabetes, using the Glide Solid Dose Injector technology
Lipoxen PLC (AIM:LPX), a bio-pharmaceutical company specialising in the development of high value differentiated biologicals, vaccines and siRNA delivery, announces today that it has entered into an agreement with Glide Pharma, a specialty pharmaceutical company developing products based on its proprietary needle-free drug delivery technology, the Glide SDITM. The agreement is to investigate the delivery of Lipoxen’s long-acting proprietary insulin, SuliXen, which is a conjugate of insulin with polysialic acid, using the Glide SDI.
SuliXen has already shown to be safe and well tolerated in a Phase I study and the long-acting formulation of SuliXen makes this approach very attractive for the administration of insulin. This needle-free injection could also be a key competitive advantage for SuliXen as it would meet the clear demand from patients and physicians for improved forms of insulin, which have, in particular, more patient convenience.
Under the terms of the agreement Lipoxen will provide Glide Pharma with SuliXen which Glide Pharma will then incorporate into its proprietary Glide SDI, needle-free, drug delivery technology which offers the prospect of a safe, patient friendly, solution for the administration of drugs and vaccines. Financial details were not disclosed.
M. Scott Maguire, CEO of Lipoxen, said:
“We are delighted to be able to announce this collaboration with Glide Pharma. SuliXen's reduced dosing regime already suggests it has the potential to become a recognised competitor in the $12 billion insulin market. Couple this with a less invasive, easy to use, patient friendly delivery system, and we believe you have a product that may revolutionalise insulin treatment for patients and treating physicians in the future.”
“This transaction highlights our ability to execute collaboration deals with very real commercial potential. The needle-free delivery will open up a wide range of therapeutic options for our candidates and would provide further validation of the possible wide application of Lipoxen’s proprietary PolyXen molecules. This is a very exciting time for Lipoxen, and its technologies, and I am confident this collaboration will produce additional value for shareholders.”
Dr Charles Potter, CEO of Glide Pharma, said:
“We are very pleased to be collaborating with Lipoxen on a long-acting insulin product. With an estimated 170 million people worldwide suffering from diabetes this product could make a real impact on the management of diabetes in the future, particularly in type 2 diabetes.”
